Analysis

Cook got in on the fun of the Bills' second straight 40-plus-point barrage, crossing the goal line on the ground from six and 41 yards out in the second and third quarters, respectively. The third-year pro has two of his three 100-yard efforts on the season within the last three games, and his receiving yardage total Sunday was his highest since Week 3. Cook draws a highly favorable matchup against the Patriots at home in Week 16.

Analysis

Josh Allen was the entire Buffalo offense, as he led the team in rushing attempts and yards while also scoring a trio of times on the ground from one yard away. Allen's usage combined with a negative game script left little opportunity for Cook, who saw his fewest rushing attempts of the season. More concerning was his lack of involvement as a receiver despite Allen taking to the air 37 times. Cook has now failed to reach 50 rushing yards in four of his last seven games.

Analysis

Cook outraced San Francisco's defense down the sideline for a 65-yard rushing touchdown in the second quarter after watching Ray Davis cap the previous drive with a five-yard touchdown run. Buffalo's run-heavy game script helped Cook exceed 100 rushing yards for only the second time this season, as he came four yards short of his Week 8 season high against the Seahawks. Cook also raised his rushing touchdown total to 11, which is a marked improvement from his two rushing touchdowns apiece in 2022 and 2023. He'll look to continue his success against NFC West competition in Week 14 against the Rams.

Analysis

Cook struggled on the ground against the interior of the Chiefs' defense, as many talented backs have against the third-ranked rushing defense this season. However, the 25-year-old made an impact in the box score by finishing off a pair of lengthy offensive drives in the first half with short trips to the end zone. It was the Georgia product's worst yardage output of the season but not his worst fantasy showing. Cook has generated 751 yards from scrimmage with 11 combined touchdowns in 10 starts as the Bills enter a bye week before hosting the 49ers on Dec. 1.

Analysis

Cook worked hard for his yards Sunday, considering 20 of them came on one carry. However, that explosive play and his two-yard game-sealing touchdown run with just over three minutes remaining helped round out his fantasy day, and he now has four rushing scores in the last four games. While he surprisingly was quiet in the passing game despite the Bills being down multiple targets Sunday, Cook should remain busy as both a runner and receiver in a Week 11 home showdown against the Chiefs.

Analysis

Cook got 10 of the 17 rushing attempts among Buffalo's running backs, but backups Ray Davis and Ty Johnson were both more efficient in terms of yards per carry, and Davis had a 63-yard receiving touchdown. Cook has been feast or famine on the ground, with four games of at least 71 rushing yards and four games of 32 or fewer heading into Week 10 against the Colts. He has seven rushing touchdowns this season after scoring only four times on the ground across the 2022 and 2023 regular seasons combined.

Analysis

Cook was the star on offense in a one-sided affair Sunday, running roughshod over Seattle's porous rushing defense en route to two scores. The 24-year-old had already scored twice in a game this season, but this was his first 100-plus-yard rushing contest in 2024. Cook has now produced a combined 597 yards from scrimmage with eight total touchdowns through seven games, making him an elite fantasy tailback heading into next Sunday's tilt against Miami.

Analysis

Cook returned from a one-game absence and retook the lead-back role in Buffalo's backfield, accounting for 12 of 17 carries by running backs. His efficiency was a more significant reason for concern, as his longest gain went for 11 yards while seven of his attempts went for two yards or fewer. Even more of a problem for Cook was his lack of involvement in the passing game, as he went without both a target and a reception in a game for the first time this season.

Analysis

Prior to Cook sitting out this past Monday against the Jets, there wouldn't have been much worry about his workload, as he was averaging 16.2 touches for 86.4 yards from scrimmage and 1.0 touchdown per game through five weeks. However, a toe injury for Cook paved the way for Davis to lead the Bills backfield Week 6, and the latter reeled off 152 total yards on 23 touches. Cook's health took a turn for the better this week, when he capped it with back-to-back full practices, while Davis came down with a calf issue Thursday and logged a pair of limited sessions. Even if Davis is able to earn active status Sunday, Cook should regain his usual role in Buffalo's offense.