Analysis

Cook's yardage plummeted after he rushed for at least 100 yards in three of the previous four games. He ran in a one-yard touchdown in the third quarter for his 15th rushing touchdown of the campaign. Cook may not get a chance to add to that total in Week 18 against the Patriots since Buffalo has locked in the No. 2 seed and could rest its starters.

Analysis

Cook turned the game around for Buffalo by scoring consecutive touchdowns in the second and third quarters. The first came on an explosive 46-yard scamper through the middle of the New England defense while he broke through several arm tackles. He then caught a short, four-yard touchdown to tie the game. Despite being limited to around 15 touches per matchup, Cook has eclipsed 100 yards from scrimmage in three of four contests while finding the end zone a total of five times since Buffalo's Week 12 bye.

Analysis

Cook got in on the fun of the Bills' second straight 40-plus-point barrage, crossing the goal line on the ground from six and 41 yards out in the second and third quarters, respectively. The third-year pro has two of his three 100-yard efforts on the season within the last three games, and his receiving yardage total Sunday was his highest since Week 3. Cook draws a highly favorable matchup against the Patriots at home in Week 16.

Analysis

Josh Allen was the entire Buffalo offense, as he led the team in rushing attempts and yards while also scoring a trio of times on the ground from one yard away. Allen's usage combined with a negative game script left little opportunity for Cook, who saw his fewest rushing attempts of the season. More concerning was his lack of involvement as a receiver despite Allen taking to the air 37 times. Cook has now failed to reach 50 rushing yards in four of his last seven games.

Analysis

Cook outraced San Francisco's defense down the sideline for a 65-yard rushing touchdown in the second quarter after watching Ray Davis cap the previous drive with a five-yard touchdown run. Buffalo's run-heavy game script helped Cook exceed 100 rushing yards for only the second time this season, as he came four yards short of his Week 8 season high against the Seahawks. Cook also raised his rushing touchdown total to 11, which is a marked improvement from his two rushing touchdowns apiece in 2022 and 2023. He'll look to continue his success against NFC West competition in Week 14 against the Rams.

Analysis

Cook struggled on the ground against the interior of the Chiefs' defense, as many talented backs have against the third-ranked rushing defense this season. However, the 25-year-old made an impact in the box score by finishing off a pair of lengthy offensive drives in the first half with short trips to the end zone. It was the Georgia product's worst yardage output of the season but not his worst fantasy showing. Cook has generated 751 yards from scrimmage with 11 combined touchdowns in 10 starts as the Bills enter a bye week before hosting the 49ers on Dec. 1.

Analysis

Cook worked hard for his yards Sunday, considering 20 of them came on one carry. However, that explosive play and his two-yard game-sealing touchdown run with just over three minutes remaining helped round out his fantasy day, and he now has four rushing scores in the last four games. While he surprisingly was quiet in the passing game despite the Bills being down multiple targets Sunday, Cook should remain busy as both a runner and receiver in a Week 11 home showdown against the Chiefs.

Analysis

Cook got 10 of the 17 rushing attempts among Buffalo's running backs, but backups Ray Davis and Ty Johnson were both more efficient in terms of yards per carry, and Davis had a 63-yard receiving touchdown. Cook has been feast or famine on the ground, with four games of at least 71 rushing yards and four games of 32 or fewer heading into Week 10 against the Colts. He has seven rushing touchdowns this season after scoring only four times on the ground across the 2022 and 2023 regular seasons combined.

Analysis

Cook was the star on offense in a one-sided affair Sunday, running roughshod over Seattle's porous rushing defense en route to two scores. The 24-year-old had already scored twice in a game this season, but this was his first 100-plus-yard rushing contest in 2024. Cook has now produced a combined 597 yards from scrimmage with eight total touchdowns through seven games, making him an elite fantasy tailback heading into next Sunday's tilt against Miami.