Analysis

Kittle came out of a Week 10 win at Tampa Bay with hamstring irritation that capped him to a pair of limited practices during Week 11 prep. While he ultimately was inactive for Sunday's loss to the Seahawks, Shanahan noted the tight end was "close" to being able to suit up. Kittle's activity level Wednesday may set the tone for the rest of the week, but it appears as if he'll miss just one game as a result of the injury.

Analysis

Kittle has dealt with a few injuries this season, including a hamstring issue that capped him to two limited practices during Week 11 prep and left him questionable for Sunday's game. Having said that, Adam Schefter of ESPN reported early Sunday morning that Kittle wasn't likely to play, with his availability subject to a pregame warmup. With inactive status now confirmed for Kittle, he'll miss his second contest of the campaign. Per Nick Wagoner of ESPN.com, fellow TE Eric Saubert is dealing with an illness but expected to play, which could mean Jake Tonges and Brayden Willis get more snaps at the position than expected.

Analysis

The 49ers will see how he feels pregame, but at this stage, the team isn't optimistic that Kittle will be able to play still be a chance he can play. Official word on Kittle's status will arrive 90 minutes prior to the 4:05 p.m. ET kickoff, when the 49ers release their inactive list. After handling a normal snap count in the 49ers' Week 10 win over the Buccaneers, Kittle sat out Wednesday's practice with the hamstring injury, then was a limited practice participant Thursday and Friday. Eric Saubert would likely start at tight end if Kittle is inactive, but he would serve primarily as a blocker and wouldn't be nearly as involved as Kittle in the passing game.

Analysis

Kittle was a limited practice participant Thursday and Friday after sitting out Wednesday. 49ers coach Kyle Shanahan said Wednesday that he expects Kittle to play, but fantasy managers will still want to make sure the tight end avoids the inactive list ahead of a 4:05 p.m. ET kickoff Sunday. Eric Saubert likely will step in as the starter if Kittle ends up inactive.

Analysis

Before Kittle was held out of Wednesday's session due to what has been termed hamstring irritation by Kyle Shanahan, the coach himself relayed little concern about the tight end's potential to play Sunday against the Seahawks, per Nick Wagoner of ESPN.com. Kittle took a step in the right direction Thursday, but he still may need to log a full practice Friday in order to head into the weekend sans a designation.

Analysis

Kittle has tended to a variety of health concerns this season, including hamstring, rib and foot issues. Shanahan has referred to Kittle's current issue as hamstring irritation, but there's an expectation that the tight end will take part in drills Thursday. Kittle's ensuing activity level thus will be of interest as the 49ers continue Week 11 prep.

Analysis

Shanahan relayed Monday that Kittle was dealing with hamstring irritation, which will keep the tight end out of the first session of the week. Kittle has played through hamstring, rib and foot injuries this season, missing only one game (Week 3) as a result, but it's unclear if he may be in danger of another absence in Week 11. His activity in practices Thursday and Friday likely will provide some insight into his odds to play Sunday against the Seahawks.

Analysis

Kittle has been listed with hamstring, rib and foot issues on injury reports this season, but he's still logged more than 85 percent of the offensive snaps in seven of his eight appearances en route to a cumulative 43-560-7 line on 53 targets. Shanahan said the current health concern will be watched as the week continues, putting Kittle's status for Sunday's game against the Seahawks at least somewhat in question.

Analysis

Kittle continued his dominant fantasy campaign by scoring his seventh touchdown through eight active games. The star tight end had picked up the slack offensively while the 49ers suffered multiple injuries to key players over the first half of the season. With the team welcoming back star tailback Christian McCaffrey (Achilles) on Sunday, it was a positive sign to see the tight end still posting big fantasy numbers as the offense returns to full strength. Kittle continues to be one of the top options at his position heading into a Week 11 matchup against Seattle.